drugset / Trial / NCT06699342
Pacing of Left Bundle Branch Area and Atroventricular Node ablatIon in Patients With Symptomatic Atrial Fibrillation
RandomizedParallel-groupOpen-labelTreatment
Summary
This study aimed to compare the clinical outcomes of left bundle branch area pacing combined with atrioventricular node ablation and pharmacologic treatment optimized according to guidelines in patients with symptomatic atrial fibrillation refractory or intolerant to drug therapy or catheter ablation.
Timeline
- Start
- 2025-01-27
- Primary completion
- 2027-12-31
- Completion
- 2027-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amiodarone | Small molecule | — | — |
| Comparator | Apixaban | Small molecule | — | — |
| Comparator | Bisoprolol | Other / unclassified | — | — |
| Comparator | Diltiazem | Small molecule | — | — |
| Comparator | Dronedarone | Small molecule | — | — |
| Comparator | flecainide | Small molecule | — | — |
| Comparator | propafenone | Unknown | — | — |