drugset / Trial / NCT06708455

Phase 2b of RAPA-201 Cell Therapy in Post-PD-(L)-1 Melanoma

NCT06708455

Phase 2 Not yet recruiting 65 enrolled Rapa Therapeutics LLC
NaSingle-groupOpen-labelTreatment

Summary

The protocol is a Simon's 2-stage, non-randomized, open label, multi-site, phase 2 trial for patients with advanced metastatic, recurrent and unresectable malignant melanoma that has recurred or relapsed after prior anti-PD-(L)1 therapy.

Timeline

Start
2027-03-01
Primary completion
2029-03-01
Completion
2029-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject RAPA-201 Cell therapy 8e+07 cells
Subject RAPA-201 Cell therapy 4e+08 cells
Background Carboplatin Small molecule
Background Paclitaxel Small molecule

Indications