drugset / Trial / NCT06708455
Phase 2b of RAPA-201 Cell Therapy in Post-PD-(L)-1 Melanoma
NaSingle-groupOpen-labelTreatment
Summary
The protocol is a Simon's 2-stage, non-randomized, open label, multi-site, phase 2 trial for patients with advanced metastatic, recurrent and unresectable malignant melanoma that has recurred or relapsed after prior anti-PD-(L)1 therapy.
Timeline
- Start
- 2027-03-01
- Primary completion
- 2029-03-01
- Completion
- 2029-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | RAPA-201 | Cell therapy | 8e+07 cells | — |
| Subject | RAPA-201 | Cell therapy | 4e+08 cells | — |
| Background | Carboplatin | Small molecule | — | — |
| Background | Paclitaxel | Small molecule | — | — |