drugset / Trial / NCT06710990
Investigation of Drug-drug Interaction of Ritonavir and Itraconazole on the Pharmacokinetics of SHR-A1811 in Subjects With HER2-expressing Advanced Breast Cancer
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The study is being conducted to evaluate the pharmacokinetics and safety of SHR-A1811 monotherapy and in combination with Ritonavir or Itraconazole in subjects with HER2-expressing advanced breast cancer.
Timeline
- Start
- 2025-02-17
- Primary completion
- 2025-10-15
- Completion
- 2025-10-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itraconazole | Small molecule | — | — |
| Subject | Ritonavir | Other / unclassified | — | — |
| Subject | SHR-A1811 | Monoclonal antibody | — | — |