drugset / Trial / NCT06715709

How Many Dexamethasone Doses Should Be Given Perioperatively?

NCT06715709 ↗

Phase 4 Enrolling by invitation 339 enrolled Mayo Clinic
RandomizedParallel-groupSingle-blindPrevention

Summary

The purpose of this study is to determine the most efficient and safest dexamethasone dose given perioperatively during total knee arthroplasty that reduces postoperative option consumption and pain, improves postoperative nausea and vomiting, and minimizes postoperative complications

Timeline

Start
2025-03-25
Primary completion
2027-01-01
Completion
2027-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 8 mg Intravenous
Subject Dexamethasone Small molecule 16 mg Intravenous

Indications