Role of Ondansetron in Spinal Anaesthesia Induced Hypotension

Phase 2/3 Not yet recruiting 160 enrolled Assiut University

RandomizedCrossoverSingle-blindPrevention

Summary

The objective of this study is to determine the effect of ondansetron on the total consumption of norepinephrine infusion needed to prevent spinal anaesthesia induced hypotension in cesarean section.

Timeline

Start: 2025-01-01
Primary completion: 2026-12-01
Completion: 2027-02-01

Publications

Results Sheng ZM, Sun HQ, Mao JQ, Liu J, Liang G, Mei Z. Comparative dose-response study on the infusion of norepinephrine combined with intravenous ondansetron versus placebo for preventing hypotension during spinal anesthesia for cesarean section: a randomised controlled trial. Int J Surg. 2024 Feb 1;110(2):832-838. doi: 10.1097/JS9.0000000000000920.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ondansetron	Other / unclassified	0.1 mg/kg	Intravenous

Indications

No indication recorded.