drugset / Trial / NCT06728033

Fascia Iliaca Compartment Block and Tramadol for Analgesia in Hip Fracture

NCT06728033

Not yet recruiting 240 enrolled West China Hospital
RandomizedParallel-groupSingle-blindTreatment

Summary

Hip fractures are a growing public health concern globally due to the aging population, with high incidence and significant mortality rates one year post-fracture. Effective pain management is critical to improving outcomes and accelerating recovery. Tramadol, a widely used intravenous analgesic, has dual opioid and non-opioid mechanisms but is associated with side effects, such as nausea, dizziness, and respiratory depression, necessitating careful monitoring in hip fracture patients. The supra-inguinal fascia iliaca compartment block (SiFICB) offers a promising alternative, targeting key nerves to achieve effective analgesia through ultrasound-guided delivery of local anesthetics. SiFICB minimizes side effects and improves pain control by accurately blocking the femoral, lateral femoral cutaneous, and obturator nerves. While its postoperative benefits are well-documented, its efficacy in managing preoperative pain from hip fractures remains underexplored. This study hypothesizes that ultrasound-guided SiFICB provides superior perioperative analgesia compared to intravenous tramadol. A prospective randomized controlled trial will evaluate the analgesic efficacy of SiFICB, using the numerical rating scale (NRS) to assess pain, aiming to improve the management of hip fracture-related pain and patient outcomes.

Timeline

Start
2025-01-01
Primary completion
2027-05-31
Completion
2027-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Tramadol Other / unclassified 2 mg/kg Intravenous

Indications