drugset / Trial / NCT06733285
Clinical Study to Investigate the Ability of a Stannous Fluoride Toothpaste to Protect From Dentine Hypersensitivity
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of this study is to investigate and characterize the Dentine Hypersensitivity (DH) protection profiles of a 0.454 percent (%) Stannous Fluoride (SnF2) toothpaste and a regular fluoride toothpaste, in response to evaporative air (Schiff sensitivity score) and tactile (tactile threshold in grams \[g\]) stimuli, with twice daily brushing over 2 weeks.
Timeline
- Start
- 2025-02-04
- Primary completion
- 2025-05-27
- Completion
- 2025-05-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Colgate Cavity Protection | Unknown | 1000 ppm | Topical |
| Subject | stannous fluoride | Small molecule | 0.454 % | Topical |
| Subject | stannous fluoride | Small molecule | 1100 ppm | Topical |