drugset / Trial / NCT06738043

Dexmedetomidine Versus Ketamine as Adjuvants in Bariatric Surgery

NCT06738043

Not yet recruiting 90 enrolled Tanta University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This randomized controlled trial aims to compare the analgesic efficacy of dexmedetomidine infusion versus low-dose ketamine infusion as adjuvants in bariatric surgery. The study includes 90 patients undergoing bariatric surgery at Menoufia University Hospital, randomized into three groups: dexmedetomidine, ketamine, and control (placebo). Primary outcomes include total morphine consumption intra- and post-operatively. Secondary outcomes include postoperative pain scores, total analgesic consumption, time to first analgesic request, hemodynamic parameters, and patient satisfaction. This study seeks to explore safer, more effective pain management strategies to minimize opioid use in bariatric surgery patients.

Timeline

Start
2026-04-20
Primary completion
2027-04-20
Completion
2027-04-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified 0.5 ug/kg
Subject Ketamine Small molecule 0.3 mg/kg

Indications