drugset / Trial / NCT06742853
A Study to Investigate the Pharmacokinetics, Safety, Tolerability, and Efficacy of AZD0780 With Ezetimibe Combinations in Healthy Adults With Elevated LDL-C.
RandomizedParallel-groupSingle-blindTreatment
Summary
The main aim of this study is to assess the effects of AZD0780 when added on top of ezetimibe or ezetimibe and rosuvastatin or ezetimibe and bempedoic acid.
Timeline
- Start
- 2024-12-20
- Primary completion
- 2025-10-29
- Completion
- 2025-10-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Laroprovstat | Small molecule | — | Oral |
| Background | Bempedoic acid | Small molecule | 180 mg | Oral |
| Background | Ezetimibe | Unknown | 10 mg | Oral |
| Background | Rosuvastatin | Small molecule | 20 mg | Oral |