drugset / Trial / NCT06748638

Clinical Study on the Application of Lactulose Combined with Linaclotide in Bowel Preparation for Colonoscopy

NCT06748638

Phase 4 Enrolling by invitation 444 enrolled Haifeng Lan
RandomizedParallel-groupSingle-blindSupportive care

Summary

This is a single-center, single-blind, randomized controlled clinical study. Participants meeting the inclusion criteria were randomly assigned to lactulose + linaclotide group, lactulose group, and PEG group in equal proportion. In this study, the effectiveness, tolerability, adverse reactions and prognosis of three intestinal preparation regimens: lactulose -linalotide group, lactulose group and PEG group were compared by evaluating the intestinal cleanliness rate (BBPS score) of patients and quantitative analysis of intestinal bubble under colonoscopy, with a view to improving the intestinal cleanliness rate of colonoscopy subjects.

Timeline

Start
2024-09-01
Primary completion
2025-10-01
Completion
2025-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Lactulose Other / unclassified 15 ml Oral
Subject Linaclotide Peptide 290 ug Oral
Subject polyethylene glycol Other / unclassified 137.15 g Oral

Indications

No indication recorded.