drugset / Trial / NCT06788509

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

NCT06788509

Phase 1 Enrolling by invitation 120 enrolled Janssen Research & Development, LLC
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to collect long-term safety data in participants with cancers including acute myeloid leukemia, non-Hodgkin lymphoma, myelodysplastic syndrome, chronic lymphocytic leukemia (type of cancer of the blood and bone marrow in which the bone marrow makes a large number of abnormal blood cells) and advanced solid tumors and metastatic castration-resistant prostate cancer (mCRPC).

Timeline

Start
2024-12-30
Primary completion
2028-01-19
Completion
2028-10-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Ibrutinib Small molecule Oral
Subject JNJ-64264681 Small molecule Oral
Subject JNJ-70218902 Other / unclassified Oral
Subject JNJ-74856665 Unknown Oral
Subject JNJ-80948543 Unknown Subcutaneous
Subject JNJ-87801493 Unknown Subcutaneous
Subject ONAMETOSTAT Small molecule Oral
Subject REZETAMIG Monoclonal antibody Subcutaneous
Subject SAFIMALTIB Small molecule Oral