drugset
drugset / Trial / NCT06789549

Epinephrine Nasal Drops for Epistaxis During Nasal Intubation

NCT06789549 ↗

Phase 2 Completed 40 enrolled Padjadjaran University
RandomizedParallel-groupTriple-blindPrevention

Summary

Epistaxis is the most common complication of nasotracheal intubation. Incidence of epistaxis during nasotracheal intubation ranges from 22% to 80%. Epistaxis during nasotracheal intubation can lead to several complications such as nasal discomfort, airway obstruction, and blood aspiration. The most commonly used and available topical vasoconstrictor in drop form is oxymetazoline. However, oxymetazoline may not always be available in some hospitals, so epinephrine can be used as an alternative nasal decongestant to reduce the incidence of epistaxis during nasotracheal intubation.

Timeline

Start
2024-01-01
Primary completion
2024-03-20
Completion
2024-04-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Epinephrine Other / unclassified 0.1 % Other
Subject Epinephrine Other / unclassified 1 ml Other
Comparator Oxymetazoline Other / unclassified 0.05 % Other
Comparator Oxymetazoline Other / unclassified 1 ml Other

Indications

No indication recorded.