drugset / Trial / NCT06809751

Evaluating Efficacy and Safety of Oral Melatonin in Acute Central Serous Chorioretinopathy

NCT06809751

Phase 2/3 Not yet recruiting 48 enrolled Mohsen Pourazizi
RandomizedParallel-groupDouble-blindTreatment

Summary

The goal of this clinical trial is to learn if oral melatonin can enhance visual acuity and central macular thickness in central serous chorioretinopathy (CSCR) in adults. The main questions it aims to answer are: 1. How does melatonin affect central macula thickness in CSCR? 2. How does melatonin affect visual acuity in CSCR? Researchers will compare placebo (a look-like substance that contains no drug) to see if melatonin works to treat CSCR. Participants will: 1. Take melatonin or placebo twice a day for one month 2. Visit the clinic after finishing a course of treatment, and 1 and 3 months after that for visual acuity assessment and tests 3. Keep a diary of their symptoms

Timeline

Start
2025-02-01
Primary completion
2025-05-01
Completion
2025-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Melatonin Small molecule 3 mg Oral