drugset / Trial / NCT06810765
Trifecta Research Study
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The Special Operations Care-Fund (SOC-F) will sponsor the application of four treatments - hormone replacement, magnetic resonance brain stimulation, ibogaine, and 5-Meo-DMT - to Special Operations Forces veterans with a history of combat deployments, traumatic brain injury, and problems with mental health and cognitive functioning. An observational study will be conducted in parallel by the Johns Hopkins Center for Psychedelic and Consciousness Research to determine the effectiveness and safety of each treatment, primarily through measuring post-treatment changes in PTSD symptoms and cognitive functioning.
Timeline
- Start
- 2025-09
- Primary completion
- 2026-12
- Completion
- 2027-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ibogaine | Small molecule | — | — |
| Subject | Mebufotenin | Small molecule | — | — |
| Background | Magnesium Sulfate | Other / unclassified | — | — |