drugset / Trial / NCT06824792

Optimal Standard Treatment Selection for Solid Tumor Patients by Biologically-informed Multi-agent System

NCT06824792

Phase 4 Not yet recruiting 3000 enrolled NING LI
NaSingle-groupOpen-labelTreatment

Summary

This study is an exploratory cohort study conducted under real-world conditions, aiming to evaluate the feasibility of an artificial intelligence (AI)-guided standard treatment selection model for advanced solid tumors, as well as its superiority compared to clinician-selected treatment plans. A multi-agent system based on multimodal AI models will rank the priority of standard treatment options based on the personalized information of the patients, including including demographics, clinical information, and multi-omics data. The final treatment plan will be jointly selected by the patient and the clinician from the AI-recommended options, thereby delivering a personalized treatment.

Timeline

Start
2025-03-01
Primary completion
2028-02-29
Completion
2030-02-28

Drugs

EvaluationDrugModalityDoseRoute
Background Osimertinib Small molecule
Background Pembrolizumab Monoclonal antibody
Background Pemetrexed Small molecule

Indications