drugset / Trial / NCT06848699

A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors

NCT06848699

Phase 1/2 Recruiting 105 enrolled Shanghai Henlius Biotech
RandomizedSequentialOpen-labelTreatment

Summary

The study is being conducted to explore the reasonable dosage and evaluate the efficacy, safety and tolerability of HLX43 (Anti-PD-L1 ADC) in combination with Serplulimab (anti-PD-1 humanized monoclonal antibody injection) in patients with advanced/metastatic solid tumors

Timeline

Start
2025-02-25
Primary completion
2026-10-30
Completion
2027-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject HLX43 Other / unclassified Intravenous
Subject Serplulimab Monoclonal antibody 300 mg Intravenous