drugset / Trial / NCT06853184
Study Evaluating the Efficacy and Safety of Artesunate
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is a randomized, open-label, active comparator-controlled, dose-ranging trial of the efficacy and safety of IV artesunate in combination with IV GCV or oral VGCV and SOC treatment compared to GCV or VGCV monotherapy and SOC treatment in SOT recipients with clinically significant CMV infection.
Timeline
- Start
- 2025-08-01
- Primary completion
- 2028-05-31
- Completion
- 2028-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Artesunate | Small molecule | 2.4 mg/kg | Intravenous |
| Subject | Artesunate | Small molecule | 4.8 mg/kg | Intravenous |
| Comparator | Ganciclovir | Small molecule | — | — |
| Comparator | Valganciclovir | Small molecule | — | — |