drugset / Trial / NCT06857279

A Phase II Clinical Study to Evaluate HLX43 in Subjects With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

NCT06857279

Phase 2 Recruiting 167 enrolled Shanghai Henlius Biotech
RandomizedParallel-groupOpen-labelTreatment

Summary

The study is being conducted to to explore the reasonable dosage and evaluate the efficacy, safety and tolerability of HLX43 (Anti-PD-L1 ADC) in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)

Timeline

Start
2025-04-22
Primary completion
2027-12-30
Completion
2029-01-30

Drugs

EvaluationDrugModalityDoseRoute
Subject HLX43 Other / unclassified Intravenous
Subject PIMURUTAMAB Monoclonal antibody
Subject Serplulimab Monoclonal antibody