Clinical Trial of Mexiletine Hydrochloride for Spinal and Bulbar Muscular Atrophy

Summary

The purpose of this clinical trial is to evaluate the efficacy and safety of mexiletine hydrochloride in patients with spinal and bulbar muscular atrophy. The main questions it aims to answer are: Does mexiletine hydrochloride improve the ALSFRS-R score in spinal and bulbar muscular atrophy patients? Participants will: Take mexiletine hydrochloride or a placebo every day for 3 months Visit the hospital once every 4 weeks for evaluations.

Timeline

Start

2025-02-28

Primary completion

2027-12-31

Completion

2027-12-31

Drugs

Indications