drugset / Trial / NCT06864988

4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

NCT06864988

Phase 3 Active not recruiting 480 enrolled 4D Molecular Therapeutics
RandomizedParallel-groupQuadruple-blindTreatment

Summary

A Phase 3, Randomized, Double-Masked, Active-Controlled Trial in Adults with Macular Neovascularization Secondary to Age-Related Macular Degeneration

Timeline

Start
2025-03-03
Primary completion
2027-06
Completion
2028-06

Drugs

EvaluationDrugModalityDoseRoute
Subject 4D-150 Gene therapy (AAV / viral vector) 3e+10 vg Intravitreal
Comparator Aflibercept Protein / enzyme biologic 2 mg Intravitreal