drugset / Trial / NCT06868576

PPOS Protocol Versus GnRH Anatagonist for Expected Normal Responder Patients Undergoing ART : a Randomized Clinical Trial

NCT06868576

Phase 3 Completed 328 enrolled Kasr El Aini Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

The aim of this study is to compare the efficacy and safety of Progestin-Primed Ovarian Stimulation (PPOS) protocol versus the fixed GnRH antagonist protocol in expected normal responder patients undergoing intracytoplasmic sperm injection (ICSI) with frozen-thawed embryo transfer (FET). By evaluating key clinical outcomes, including ovarian response, embryological parameters, and pregnancy rates, this study seeks to determine the relative advantages and limitations of each protocol.

Timeline

Start
2023-01-03
Primary completion
2024-10-31
Completion
2025-02-28

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cetrorelix Other / unclassified
Subject Dydrogesterone Other / unclassified 20 mg Oral

Indications

No indication recorded.