drugset / Trial / NCT06876870

MR-Evaluation of Renal Function in Anesthetized Pediatric Patients

NCT06876870

Phase 4 Not yet recruiting 50 enrolled Uppsala University Uppsala University Hospital · collab
RandomizedParallel-groupSingle-blindBasic science

Summary

The goal of this study is to investigate the effect of the anesthetic agents sevoflurane or propofol on the blood flow and oxygen delivery to the kidneys. Pediatric patients who are planned to undergo an MRI scan with generalized anesthesia will be randomized to either IV anesthesia with propofol or inhalation anesthesia with sevoflurane. Both of these anesthetic methods are commonly used for anesthesia on an everyday basis. In addition to the clinically indicated MRI, Multiparametric MRI will be performed to visualize the effect of the anesthetic agent on renal blood flow, perfusion and oxygenation.

Timeline

Start
2025-10-01
Primary completion
2026-12-10
Completion
2027-06-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Propofol Small molecule Intravenous
Comparator Sevoflurane Other / unclassified Inhaled

Indications

No indication recorded.