drugset / Trial / NCT06883123
Efficacy of Simbrinza and Rocklatan vs Cosopt and Latanoprost
RandomizedParallel-groupQuadruple-blindBasic science
Summary
A randomized, multi-site, parallel-group, prospective study of patients who are adults with a diagnosis of mild to moderate open-angle glaucoma (OAG), currently on an on-label use of combination topical medication of Cosopt and Latanoprost for a minimum of 1 month.
Timeline
- Start
- 2025-05-14
- Primary completion
- 2026-04-01
- Completion
- 2026-04-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Brimonidine | Small molecule | 0.2 % | Topical |
| Subject | Brinzolamide | Small molecule | 1 % | Topical |
| Comparator | Dorzolamide | Small molecule | 2 % | Topical |
| Comparator | Latanoprost | Small molecule | 0.005 % | Topical |
| Subject | Netarsudil | Small molecule | 0.02 % | Topical |
| Comparator | Timolol | Other / unclassified | 0.5 % | Topical |