drugset / Trial / NCT06899061
Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib
RandomizedCrossoverOpen-labelOther
Summary
A Phase I modular study to assess the effect of oral saruparib on other treatments in patients with advanced solid malignancies.
Timeline
- Start
- 2025-03-25
- Primary completion
- 2026-02-03
- Completion
- 2028-05-19
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Digoxin | Other / unclassified | — | Oral |
| Comparator | Furosemide | Other / unclassified | — | Oral |
| Comparator | Metformin | Small molecule | — | Oral |
| Comparator | Rabeprazole | Small molecule | — | Oral |
| Comparator | Rosuvastatin | Small molecule | — | Oral |
| Comparator | Saruparib | Small molecule | — | Oral |