drugset / Trial / NCT06906887

PULSO Trial: Pulsed Low-Dose-Rate (PLDR) Radiation Chemoradiation (CRT) vs. Standard CRT for Esophageal Cancer

NCT06906887 ↗

Phase 2 Recruiting 50 enrolled Medical College of Wisconsin
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a prospective, randomized, open-label, two-arm phase 2 trial that will evaluate whether the use of Pulsed Low-Dose-Rate radiation technique, as compared to standard radiation, is associated with reduced rates of clinically significant esophagitis during and following chemoradiation.

Timeline

Start
2025-06-17
Primary completion
2030-11-01
Completion
2032-06-01

Drugs

EvaluationDrugModalityDoseRoute
Background Carboplatin Small molecule — —
Background Paclitaxel Small molecule — —

Indications