drugset / Trial / NCT06914063

Assessing Patient Comfort, Anxiety, and Satisfaction During CR Comparing Conventional Drops With ROC

NCT06914063

Active not recruiting 74 enrolled Superior University
RandomizedParallel-groupOpen-labelHealth-services research

Summary

This study aims to compare the efficacy of conventional cycloplegic agents, such as cyclopentolate, with rapid-onset cycloplegics, like a combination of tropicamide and phenylephrine, in reducing patient anxiety and discomfort during cycloplegic refraction. Cycloplegic refraction is an essential procedure for diagnosing refractive errors, particularly in children, by temporarily paralyzing the ciliary muscle to inhibit accommodation. While cyclopentolate has a relatively quick onset, tropicamide is preferred due to its faster onset and shorter duration. Despite its advantages, concerns about patient discomfort and anxiety during the procedure remain, especially in pediatric populations.

Timeline

Start
2025-03-20
Primary completion
2025-06-20
Completion
2026-02-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Phenylephrine Small molecule
Subject cyclopentolate Unknown
Subject tropicamide Small molecule

Indications