drugset / Trial / NCT06914063
Assessing Patient Comfort, Anxiety, and Satisfaction During CR Comparing Conventional Drops With ROC
RandomizedParallel-groupOpen-labelHealth-services research
Summary
This study aims to compare the efficacy of conventional cycloplegic agents, such as cyclopentolate, with rapid-onset cycloplegics, like a combination of tropicamide and phenylephrine, in reducing patient anxiety and discomfort during cycloplegic refraction. Cycloplegic refraction is an essential procedure for diagnosing refractive errors, particularly in children, by temporarily paralyzing the ciliary muscle to inhibit accommodation. While cyclopentolate has a relatively quick onset, tropicamide is preferred due to its faster onset and shorter duration. Despite its advantages, concerns about patient discomfort and anxiety during the procedure remain, especially in pediatric populations.
Timeline
- Start
- 2025-03-20
- Primary completion
- 2025-06-20
- Completion
- 2026-02-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Phenylephrine | Small molecule | — | — |
| Subject | cyclopentolate | Unknown | — | — |
| Subject | tropicamide | Small molecule | — | — |