drugset / Trial / NCT06926322
Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair
RandomizedParallel-groupDouble-blindTreatment
Summary
Management of non-vital primary molars is challenging due to the natural anatomy of primary teeth, patients' young age, and their behavior toward dental treatment. A simple and effective technique such as Lesion Sterilization and Tissue Repair offers a solution to cases with poor prognosis; however, the medicaments used in this technique have some limitations. This study will evaluate three different medicaments regarding the clinical success, radiographic success, and antibacterial activity.
Timeline
- Start
- 2025-10
- Primary completion
- 2027-08
- Completion
- 2030-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ciprofloxacin | Small molecule | 500 mg | Other |
| Comparator | Metronidazole | Small molecule | 500 mg | Other |
| Subject | chitosan-coated silver nanoparticles | Other / unclassified | — | Other |