drugset / Trial / NCT06931613

Autologous Hematopoietic Stem Cell Transplantation in Pediatric Relapsed or Refractory Hodgkin Lymphoma After Nivolumab Treatment

NCT06931613 ↗

Phase 2 Enrolling by invitation 20 enrolled St. Petersburg State Pavlov Medical University
NaSingle-groupOpen-labelTreatment

Summary

Children with relapsed or refractory Hodgkin lymphoma receive 3-6 cycles of nivolumab monotherapy. In case of achieving complete response (CR) auto-HSCT is performed. In the absence of CR, 3-6 additional cycles of nivolumab with bendamustine are administered. If complete or partial response is achieved, auto-HSCT is performed.

Timeline

Start
2022-06-01
Primary completion
2026-06-01
Completion
2027-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Nivolumab Monoclonal antibody — —