drugset / Trial / NCT06935994

Aspirin for Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease

NCT06935994

Phase 2 Recruiting 120 enrolled Taichung Veterans General Hospital
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a leading cause of chronic liver disease worldwide and a significant public health issue. MASLD may progress to liver cirrhosis and/or hepatocellular carcinoma. Although previous evidence suggests that aspirin has antisteatotic and antifibrotic effects on the liver, a randomized controlled trial assessing long-term efficacy and safety of aspirin in MASLD patients has yet to be conducted. This study aims to conduct a randomized controlled trial to evaluate the efficacy of aspirin in treating MASLD.

Timeline

Start
2025-05-05
Primary completion
2028-12-31
Completion
2032-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Aspirin Small molecule 81 mg