drugset / Trial / NCT06947811

A Study of Almonertinib Combined With Palbociclib in Patients With Advanced Solid Tumors Harboring KRAS Mutations

NCT06947811

Phase 1/2 Recruiting 71 enrolled Sun Yat-sen University
NaSingle-groupOpen-labelTreatment

Summary

The main purpose of this study is to evaluate the safety and tolerability of almonertinib combined with palbociclib in patients with advanced solid tumors harboring KRAS gene mutations, and to conduct a preliminary observation of its efficacy

Timeline

Start
2025-06-09
Primary completion
2027-03
Completion
2027-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Almonertinib Small molecule 110 mg Oral
Subject Palbociclib Small molecule 125 mg Oral

Indications