drugset / Trial / NCT06949904

The Role of Melatonin as an Adjuvant Therapy in Childhood Pneumonia

NCT06949904

Phase 1/2 Recruiting 60 enrolled Mian Muhammad Hassan Ahmed
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The goal of this study is to compare the mean length of hospital stay between children with pneumonia receiving melatonin as an adjuvant therapy and those receiving standard of care alone. The hypothesis is that combining oral melatonin with standard treatment can reduce the length of hospital stay as compared to standard of care alone. The control group will receive standard treatment (antibiotic) while the intervention group will receive standard treatment plus melatonin for 14 days.

Timeline

Start
2025-05
Primary completion
2025-12
Completion
2026-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Melatonin Small molecule 1 mg Oral
Subject Melatonin Small molecule 2.5 mg Oral
Subject Melatonin Small molecule 3 mg Oral

Indications