drugset / Trial / NCT06981767

Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen Planus

NCT06981767

Phase 2 Recruiting 42 enrolled Cairo University
RandomizedParallel-groupTriple-blindTreatment

Summary

Bromelain, an enzyme extract derived from pineapples, has shown promise due to its anti-inflammatory and wound-healing properties. However, its efficacy in treating oral mucosal ulcers remains unexplored. This study aims to provide clinical evidence on the efficacy of bromelain for managing OLP, potentially offering a safer and more effective treatment option.

Timeline

Start
2026-02-18
Primary completion
2026-07-20
Completion
2026-08-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Bromelain Protein / enzyme biologic Topical
Comparator Triamcinolone Acetonide Other / unclassified 0.1 % Topical

Indications