drugset / Trial / NCT06988488

A Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety and Preliminary Efficacy of Mezigdomide in Combination With Elranatamab in Participants With Relapsed and/or Refractory Multiple Myeloma

NCT06988488

Phase 1/2 Recruiting 62 enrolled Celgene Corporation
RandomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to evaluate the preliminary safety and determine the RP2D of mezigdomide in combination with elranatamab in participants with relapsed and refractory multiple myeloma (RRMM).

Timeline

Start
2025-10-07
Primary completion
2027-05-31
Completion
2027-06-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Mezigdomide Small molecule
Background Dexamethasone Small molecule
Background Elranatamab Monoclonal antibody

Indications