drugset / Trial / NCT06989918

MHB018A Treatment in Patients With Active Thyroid Eye Disease

NCT06989918 ↗

Phase 3 Recruiting 108 enrolled Minghui Pharmaceutical (Hangzhou) Ltd
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The primary objective of this study is to investigate the efficacy, safety, and tolerability of MHB018A, a humanized anti-IGF1R antibody, administered q4W for 6 months, in comparison to placebo, in the treatment of participants suffering from active TED.

Timeline

Start
2025-07-22
Primary completion
2026-07-31
Completion
2027-07-31

Drugs

EvaluationDrugModalityDoseRoute
Subject MHB018A Monoclonal antibody 450 mg Subcutaneous