Drugs / MHB018A
last change Jul 2026 re-read 3 minutes ago

MHB018A

Monoclonal antibody targets IGF1R via inhibition

Developed for
disease of orbital part of eye adnexa · endocrine exophthalmos
Investigated by
Minghui Pharmaceutical (Hangzhou) Ltd

Trials 6

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT07620405 Jul 2027 → Jan 2030 expected endocrine exophthalmos Minghui Pharmaceutical (Hangzhou) Ltd Not yet recruiting No outcome recorded
Phase 3 NCT07622108 Dec 2026 → Jul 2028 expected disease of orbital part of eye adnexa Minghui Pharmaceutical (Hangzhou) Ltd Not yet recruiting No outcome recorded
Phase 3 NCT07622121 Dec 2026 → Jul 2028 expected disease of orbital part of eye adnexa Minghui Pharmaceutical (Hangzhou) Ltd Not yet recruiting No outcome recorded
Phase 3 NCT07257185 Mar 2026 → Aug 2027 expected endocrine exophthalmos Minghui Pharmaceutical (Hangzhou) Ltd Recruiting No outcome recorded
Phase 3 NCT07262476 Jan 2026 → Jan 2029 expected endocrine exophthalmos Minghui Pharmaceutical (Hangzhou) Ltd Recruiting No outcome recorded
Phase 3 NCT06989918 Jul 2025 → Jul 2026 overdue disease of orbital part of eye adnexa Minghui Pharmaceutical (Hangzhou) Ltd Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as MHB018A “MHB018A 450mg for subcutaneous injection once every 4 weeks (Q4W)” NCT07620405 ↗
5

NCT07622121 ↗

NCT06989918 ↗

NCT07622108 ↗

NCT07257185 ↗

NCT07262476 ↗

Action Inhibit “inhibits the activity of a cell surface receptor called insulin-like growth factor-1 receptor (IGF-1R)” NCT07622108 ↗
Modality Monoclonal antibody “MHB018A, is a monoclonal antibody” NCT07622108 ↗
Route Subcutaneous “MHB018A 450mg for subcutaneous injection” NCT06989918 ↗
Target IGF1R “a humanized anti-IGF1R antibody” NCT06989918 ↗