drugset / Trial / NCT07257185

MHB018A Treatment in Patients With Chronic Thyroid Eye Disease

NCT07257185 ↗

Phase 3 Recruiting 150 enrolled Minghui Pharmaceutical (Hangzhou) Ltd
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The primary objective of this study is to investigate the efficacy, safety, and tolerability of MHB018A, a humanized anti-IGF1R antibody, administered Q4W for 6 months, in comparison to placebo, in the treatment of participants suffering from chronic TED.

Timeline

Start
2026-03-17
Primary completion
2027-08-31
Completion
2028-08-31

Drugs

EvaluationDrugModalityDoseRoute
Subject MHB018A Monoclonal antibody 450 mg Subcutaneous