drugset / Trial / NCT06993337
Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Recurrent Aphthous Stomatitis
RandomizedParallel-groupTriple-blindTreatment
Summary
Bromelain, a natural product, exhibits anti-inflammatory, immunomodulatory, and wound-healing properties. However, its efficacy in treating oral mucosal ulcers remains unexplored. This study aims to evaluate the effect of bromelain as a safe alternate for management of RAS.
Timeline
- Start
- 2025-06-15
- Primary completion
- 2026-05-15
- Completion
- 2026-06-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bromelain | Protein / enzyme biologic | 35 % | Topical |
| Subject | Bromelain | Protein / enzyme biologic | 50 % | Topical |
| Comparator | Triamcinolone Acetonide | Other / unclassified | 0.1 % | Topical |