drugset / Trial / NCT07001540

Evaluation of the Efficacy and Safety of Polatuzumab Vedotin Combined With Rituximab, Gemcitabine, and Oxaliplatin (Pola-R-GemOx) as Salvage Therapy for Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) Patients Ineligible for Autologous Transplantation

NCT07001540

Phase 2 Recruiting 130 enrolled Fudan University Fujian Cancer Hospital · collab
NaSingle-groupOpen-labelTreatment

Summary

This is a prospective, multicenter, single-arm clinical study designed to evaluate the efficacy and safety of Polatuzumab Vedotin combined with Rituximab, Gemcitabine, and Oxaliplatin (Pola-R-GemOx) as salvage therapy for relapsed/refractory Diffuse Large B-Cell Lymphoma (DLBCL) patients ineligible for autologous transplantation.

Timeline

Start
2025-05-08
Primary completion
2027-11-15
Completion
2027-11-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule
Subject Oxaliplatin Small molecule
Subject Polatuzumab Vedotin Other / unclassified
Subject Rituximab Monoclonal antibody