drugset / Trial / NCT07013643
A Study to Investigate the Effect of AZD6234, AZD9550, and a Combination of AZD9550 and AZD6234 on Pharmacokinetics of Combined Oral Contraceptive Ethinyl Estradiol/Levonorgestrel in Healthy Female Participants Living With Overweight or Obesity
Non-randomizedSequentialOpen-labelTreatment
Summary
This study will measure the effects of multiple doses of AZD6234, AZD9550 and a combination of AZD9550 and AZD6234 given as injection(s) on pharmacokinetics (PK) of combined oral contraceptive (CoC) ethinyl estradiol (EE)/levonorgestrel (LEVO) in healthy female participants with obesity.
Timeline
- Start
- 2025-06-04
- Primary completion
- 2027-07-09
- Completion
- 2027-07-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AZD6234 | Small activating RNA (saRNA) | — | Subcutaneous |
| Subject | AZD9550 | Other / unclassified | — | Subcutaneous |
| Subject | Levonorgestrel | Small molecule | — | Oral |
| Subject | ethinyl estradiol | Small molecule | — | Oral |
| Background | Acetaminophen | Small molecule | — | Oral |
Indications
No indication recorded.