drugset / Trial / NCT07034898
Dexmedetomidine vs Labetalol for Airway Stress in Hypertensive Craniotomy Patients
RandomizedParallel-groupDouble-blindTreatment
Summary
This randomized trial compares dexmedetomidine and labetalol in controlling airway and hemodynamic stress during extubation in hypertensive patients undergoing craniotomy. Outcomes include extubation quality, vital signs, sedation, and adverse effects.
Timeline
- Start
- 2025-04-01
- Primary completion
- 2025-08-31
- Completion
- 2025-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 0.5 ug/kg | Intravenous |
| Subject | Labetalol | Small molecule | 0.5 mg/kg | Intravenous |