drugset / Trial / NCT07041567

Low-Flow Anesthesia and Perioperative Atelectasis in Laparoscopic Bariatric Surgery

NCT07041567 ↗

Completed 60 enrolled Istanbul University
RandomizedParallel-groupTriple-blindPrevention

Summary

The goal of this clinical trial is to learn whether low-flow anesthesia reduces perioperative atelectasis compared to normal-flow anesthesia in adults undergoing laparoscopic bariatric surgery. The main questions it aims to answer are: Does low-flow anesthesia result in a smaller increase in lung ultrasound score from baseline to postoperative hour 1? Does low-flow anesthesia result in better preservation of pulmonary function at postoperative hour 48? Researchers will compare low-flow anesthesia (fresh gas flow 0.5 L/min) to normal-flow anesthesia (fresh gas flow 2 L/min) to see if low-flow anesthesia reduces the extent of perioperative atelectasis as measured by lung ultrasound. Participants will: Be randomly assigned to receive either low-flow or normal-flow inhalational anesthesia with sevoflurane during surgery Undergo lung ultrasound assessments before surgery and at postoperative hours 1 and 24 Undergo spirometric testing one day before surgery and at postoperative hour 48

Timeline

Start
2026-01-15
Primary completion
2026-04-01
Completion
2026-04-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Sevoflurane Other / unclassified 2.5 % Inhaled

Indications