drugset / Trial / NCT07046221

Tislelizumab Combined With Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma Followed by CRT or Surgery

NCT07046221

Phase 2 Not yet recruiting 60 enrolled Fujian Cancer Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

To explore the non-inferiority of the 2y-OS rate of tislelizumab combined with chemotherapy after sequential CRT in the treatment of resectable esophageal squamous cell carcinoma compared with the surgical group

Timeline

Start
2025-08-01
Primary completion
2027-08-01
Completion
2030-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule 5 unknown
Subject Cisplatin Other / unclassified 75 mg/m2
Subject Nedaplatin Small molecule 80 mg/m2
Subject Nedaplatin Small molecule 100 mg/m2
Subject Paclitaxel Small molecule 125 mg/m2
Subject Tislelizumab Monoclonal antibody 200 mg