Drugs / Albumin-Bound Paclitaxel
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Albumin-Bound Paclitaxel

Developed for
esophageal squamous cell carcinoma · non-small cell lung carcinoma · head and neck squamous cell carcinoma · gastric cancer · malignant pancreatic neoplasm · oral cavity squamous cell carcinoma · pancreatic ductal adenocarcinoma · triple-negative breast carcinoma
+16 more · biliary tract neoplasm · breast cancer · cervical cancer · cervical carcinoma · cholangiocarcinoma · colorectal cancer · esophageal cancer · gastroesophageal junction adenocarcinoma · neoplasm · non-small cell squamous lung carcinoma · oropharynx squamous cell carcinoma · pancreatic adenocarcinoma · small cell lung carcinoma · tongue squamous cell carcinoma · cancer · HER2 positive breast carcinoma
Investigated by
Shanghai Zhongshan Hospital · Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Shanghai Junshi Bioscience Co., Ltd. · Tang-Du Hospital · Tianjin Medical University Cancer Institute and Hospital · Alterome Therapeutics, Inc.
+36 more · Beijing Tongren Hospital · Bristol-Myers Squibb · CSPC Ouyi Pharmaceutical Co., Ltd. · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · First Affiliated Hospital Xi'an Jiaotong University · Fudan University · Fujian Cancer Hospital · Hao Long · Henan Cancer Hospital · HonorHealth Research Institute · Institut du Cancer de Montpellier - Val d'Aurelle · Jiangsu Hengrui Pharmaceutical Co., Ltd. · Jiangsu Simcere Pharmaceutical Co., Ltd. · Jinling Hospital, China · Junling Li · Lustgarten Foundation · Merck Sharp & Dohme LLC · Peking Union Medical College · Peking University · Peking University First Hospital · Peking University Hospital of Stomatology · Peking University People's Hospital · Peking University Shenzhen Hospital · RenJi Hospital · Second Affiliated Hospital, School of Medicine, Zhejiang University · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · Sponsor GmbH · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Sun Yat-sen University · The First Affiliated Hospital of Bengbu Medical University · The First Affiliated Hospital with Nanjing Medical University · Translational Genomics Research Institute · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Zhejiang Cancer Hospital · Zhejiang University

Trials 38

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06835569 Mar 2025 → May 2029 expected colorectal cancer, non-small cell lung carcinoma, pancreatic ductal adenocarcinoma Alterome Therapeutics, Inc. Recruiting No outcome recorded
Phase 1 NCT06020885 Aug 2023 → Oct 2025 overdue esophageal squamous cell carcinoma Sun Yat-sen University Active not recruiting No outcome recorded
Phase 1/25 trials
Phase 1/2 NCT06139211 Jan 2024 → Nov 2025 overdue neoplasm Shanghai Junshi Bioscience Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT06391190 Jan 2022 → Dec 2024 overdue cervical carcinoma RenJi Hospital Recruiting No outcome recorded
Phase 1/2 NCT04213898 Jan 2020 → Jan 2021 triple-negative breast carcinoma Henan Cancer Hospital Unknown No outcome recorded
Phase 1/2 NCT04278287 Oct 2019 → Dec 2025 overdue esophageal squamous cell carcinoma Cancer Institute and Hospital, Chinese Academy of Medical Sciences Recruiting No outcome recorded
Phase 1/2 NCT03994107 Oct 2019 → Jan 2021 breast cancer Peking Union Medical College Unknown No outcome recorded
Phase 227 trials
Phase 2 NCT07584031 Jun 2026 → Dec 2027 expected esophageal squamous cell carcinoma Tianjin Medical University Cancer Institute and Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07601737 Apr 2026 → Apr 2028 expected head and neck squamous cell carcinoma Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Recruiting No outcome recorded
Phase 2 NCT07469241 Mar 2026 → Dec 2028 expected esophageal squamous cell carcinoma Fudan University Not yet recruiting No outcome recorded
Phase 2 NCT07346807 Jan → Oct 2026 expected tongue squamous cell carcinoma Shanghai Zhongshan Hospital Not yet recruiting No outcome recorded
Phase 2 NCT06177522 Nov 2025 → Dec 2027 expected malignant pancreatic neoplasm Jinling Hospital, China Not yet recruiting No outcome recorded
Phase 2 NCT07668453 Oct 2025 → Jun 2027 expected biliary tract neoplasm The First Affiliated Hospital with Nanjing Medical University Recruiting No outcome recorded
Phase 2 NCT07046221 Aug 2025 → Aug 2027 expected esophageal squamous cell carcinoma Fujian Cancer Hospital Not yet recruiting No outcome recorded
Phase 2 NCT06770439 Apr 2025 → Jan 2027 expected pancreatic adenocarcinoma Zhejiang University Recruiting No outcome recorded
Phase 2 NCT06692491 Jan 2025 → Dec 2027 expected — Peking University Shenzhen Hospital Not yet recruiting No outcome recorded
Phase 2 NCT06725498 Dec 2024 → Nov 2026 expected head and neck squamous cell carcinoma Beijing Tongren Hospital Recruiting No outcome recorded
Phase 32 trials
Phase 3 NCT06647563 Nov 2024 → Sep 2029 expected head and neck squamous cell carcinoma Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University Not yet recruiting No outcome recorded
Phase 3 NCT05429463 Nov 2022 → Nov 2025 overdue non-small cell squamous lung carcinoma Second Affiliated Hospital, School of Medicine, Zhejiang University Recruiting No outcome recorded
Phase not applicable2 trials
— NCT07388095 Feb 2026 → Feb 2027 expected esophageal squamous cell carcinoma Tianjin Medical University Cancer Institute and Hospital Not yet recruiting No outcome recorded
— NCT05653817 Jan 2023 → Jan 2025 cholangiocarcinoma First Affiliated Hospital Xi'an Jiaotong University Unknown No outcome recorded
Comparator or background therapy30 trials
Phase 1 NCT05979818 Background Nov 2024 → Aug 2025 overdue non-small cell lung carcinoma Second Xiangya Hospital of Central South University Recruiting No outcome recorded
Phase 1 NCT04336098 Background Mar 2020 → Aug 2023 — Coherus Oncology, Inc. Completed No outcome recorded
Phase 1/2 NCT06939270 Background May 2025 → May 2027 expected cancer Chinese PLA General Hospital Not yet recruiting No outcome recorded
Phase 1/2 NCT06771622 Background Mar 2025 → Jan 2028 expected — FBD Biologics Limited Active not recruiting No outcome recorded
Phase 1/2 NCT05947487 Background Jul 2023 → Dec 2025 overdue cancer Chinese PLA General Hospital Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 68 sources stand behind the page.

FieldValueCited text
Known as Albumin-bound paclitaxel “with Toripalimab (240mg, d1), carboplatin (AUC=5, d1) + pemetrexed (500 mg/m2, d1) for patients with lung adenocarcinoma and carboplatin (AUC=5, d1) + albumin-bound paclitaxel...” NCT05962021 ↗
67

“TPF (Paclitaxel micelles or albumin-bound paclitaxel 100 mg/m2, cisplatin 30 mg/m2, fluorouracil 200 mg/m2 IV drip + 1000 mg/m2 pump for 44 hours, leucovorin/calcium 200 mg) +...” NCT07469241 ↗

“Investigator-selected chemotherapy includes injectable taxanes (paclitaxel injection, albumin-bound paclitaxel, docetaxel, etc.), irinotecan, etc., excluding oral paclitaxel solution.” NCT07552402 ↗

“Esophageal squamous cell carcinoma: cisplatin/carboplatin/nedaplatin/lobaplatin+ paclitaxel/albumin-bound paclitaxel/fluorouracil on Day 1 of each 21-day cycle for 4-6 cycles;” NCT06231680 ↗

“Enrolled participants received two cycles of induction albumin-bound paclitaxel (260 mg/m2, d1), cisplatin (60 mg/m2, d1), and toripalimab (240 mg, d1) every three weeks” PMID 42028290 ↗ Apr 2026

“Non-small cell lung cancer (squamous cell carcinoma) : paclitaxel/albumin-bound paclitaxel + carboplatin/cisplatin on Day 1 of each 21-day cycle for 4-6 cycles.” NCT06276933 ↗

“HRS-4642 in Combination With Gemcitabine and Albumin-bound Paclitaxel and Adebrelimab will be administrated per dose level in which the patients are assigned.” NCT07131514 ↗

“Albumin-bound paclitaxel 260 mg/m², carboplatin AUC = 5, intravenous infusion, Day 1, every 3 weeks for 2 cycles.” NCT07584031 ↗

“Albumin bound paclitaxel 125mg / m² followed by Gemcitabine 1000mg / m² followed by 2 weeks of rest” NCT05065801 ↗

“(Note: Gemcitabine can be replaced by docetaxel, albumin-bound paclitaxel, paclitaxel, etc.)” NCT07328854 ↗

“Albumin-bound paclitaxel 260mg/m2,on D1 IV infusion Q3W or 130mg/m2 on D1D8 IV infusion Q3W” NCT06475755 ↗

Show 57 more sources

Known as albumin paclitaxel “Although data have suggested that antiangiogenic agents may have some benefit to TNBC patients, there seems to be a lack of clinical trials evaluating efficacy and safety of...” NCT05192798 ↗
Known as Albumin-bound paclitaxel for Injection “Albumin-bound paclitaxel for Injection” NCT06939270 ↗
Known as nab-Paclitaxel “Albumin-Bound Paclitaxel /nab-Paclitaxel” NCT07668453 ↗
2

“Albumin-Bound Paclitaxel /nab-Paclitaxel” NCT07601737 ↗

“Albumin-Bound Paclitaxel /nab-Paclitaxel” NCT07432594 ↗

Route Intravenous “125 mg/m2 over 30 minutes IV infusion” NCT02754726 ↗