drugset / Trial / NCT07328854

40.2Gy Versus 49.2Gy Radiotherapy in Low-Risk Target Volume for Chemosensitive Stage II Nasopharyngeal Carcinoma

NCT07328854

Phase 3 Recruiting 346 enrolled Ming-Yuan Chen
RandomizedParallel-groupOpen-labelTreatment

Summary

This study aims to explore the efficacy and adverse events of reduced-dose radiotherapy (40.2Gy) versus conventional-dose radiotherapy (49.2Gy) to low-risk target volume for chemosensitive intermediate-stage nasopharyngeal carcinoma patients.

Timeline

Start
2025-11-20
Primary completion
2030-06-30
Completion
2032-06-30

Drugs

EvaluationDrugModalityDoseRoute
Background Cisplatin Other / unclassified 80 mg/m2 Intravenous
Background Docetaxel Small molecule
Background Gemcitabine Small molecule 1000 mg/m2 Intravenous
Background Paclitaxel Small molecule
Background Tislelizumab Monoclonal antibody 200 mg Intravenous