drugset / Trial / NCT07053215

Efficacy of Argon-Helium Cryoablation Plus PD-1 Inhibitors in NSCLC

NCT07053215

RandomizedParallel-groupOpen-labelTreatment

Summary

This randomized controlled trial investigated the efficacy and safety of argon-helium cryoablation combined with PD-1 inhibitors compared to PD-1 inhibitors plus chemotherapy for treating non-small cell lung cancer (NSCLC). The study aimed to evaluate differences in survival, tumor response, immune function, and adverse events.

Timeline

Start
2020-12-01
Primary completion
2024-12-01
Completion
2024-12-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Carboplatin Small molecule 5 unknown Intravenous
Comparator Gemcitabine Small molecule 1250 mg/m2 Intravenous
Comparator Pemetrexed Small molecule 500 mg/m2 Intravenous
Background Camrelizumab Monoclonal antibody 200 mg Intravenous