drugset / Trial / NCT07056478
RANKL Inhibition to Combat Sarcopenia in Hip Fracture Patients
RandomizedParallel-groupTriple-blindTreatment
Summary
The objective of this study is to conduct a pragmatic, randomized, double-blind, active-controlled trial to assess the efficacy of receptor activator of nuclear factor-kB ligand (RANKL) inhibition in the treatment of sarcopenia in hip fractures.
Timeline
- Start
- 2026-01-01
- Primary completion
- 2028-01-01
- Completion
- 2030-01-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Denosumab | Monoclonal antibody | 60 mg | Subcutaneous |
| Comparator | Zoledronic acid | Other / unclassified | 5 mg | Intravenous |