drugset / Trial / NCT07056478

RANKL Inhibition to Combat Sarcopenia in Hip Fracture Patients

NCT07056478

Phase 3 Not yet recruiting 130 enrolled Prince of Wales Hospital, Shatin, Hong Kong
RandomizedParallel-groupTriple-blindTreatment

Summary

The objective of this study is to conduct a pragmatic, randomized, double-blind, active-controlled trial to assess the efficacy of receptor activator of nuclear factor-kB ligand (RANKL) inhibition in the treatment of sarcopenia in hip fractures.

Timeline

Start
2026-01-01
Primary completion
2028-01-01
Completion
2030-01-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Denosumab Monoclonal antibody 60 mg Subcutaneous
Comparator Zoledronic acid Other / unclassified 5 mg Intravenous

Indications