drugset / Trial / NCT07059572
Comparative Evaluation of Guava Leaf Extract and Chlorhexidine Mouthwash in Patients With Chronic Gingivitis
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The goal of this clinical trial is to compare the effectiveness of 0.15% guava (Psidium guajava) leaf extract mouth rinse with 0.2% Chlorhexidine (CHX) mouth rinse in reducing plaque accumulation, gingival inflammation, and oral microbial load in participants with plaque-induced chronic moderate or severe gingivitis. Half of the participants will receive guava leaf extract mouth rinse, and the other half will receive Chlorhexidine(CHX).
Timeline
- Start
- 2025-05-27
- Primary completion
- 2025-10-30
- Completion
- 2025-10-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Chlorhexidine | Small molecule | 0.2 % | Oral |
| Comparator | Chlorhexidine | Small molecule | 10 ml | Oral |
| Subject | Guava leaf extract | Unknown | 0.15 % | Oral |
| Subject | Guava leaf extract | Unknown | 10 ml | Oral |