Topical Dexamethasone, Ascorbic Acid, and BGP for Enhancing Implant Osseointegration
Summary
The goal of this clinical trial was to evaluate whether the topical application of a combination of dexamethasone, ascorbic acid, and β-sodium glycerophosphate could enhance implant osseointegration in adult dental implant patients. The main question it aimed to answer was: Did the combined topical use of these agents improve implant stability during the healing phase? Researchers compared intervention implants (which received the topical agents at the implant site) to control implants (which received standard placement without topical application) within the same participant, in order to assess differences in implant stability and osseointegration. Participants: Underwent dental implant surgery. Received both the topical treatment and the standard procedure, applied to different implant sites. Returned for follow-up visits, where implant stability was measured using resonance frequency analysis (RFA) at predefined time intervals.
Timeline
- Start
- 2023-01-15
- Primary completion
- 2023-06-30
- Completion
- 2023-09-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | — | Topical |
| Subject | Vitamin C | Other / unclassified | — | Topical |
| Subject | β-Sodium Glycerophosphate | Unknown | — | Topical |
Indications
No indication recorded.