drugset / Trial / NCT07062536

mFOLFOX/mFOLFIRI vs. mFOLFOX in Advanced or Recurrent Biliary Tract Cancer Second-line

NCT07062536

Phase 2 Not yet recruiting 130 enrolled Seoul National University Bundang Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

In second line with advanced or recurrent biliary tract cancer refractory to first line gemcitabine plus cisplatin,efficacy of mFOLFOX/FOLFIRI vs mFOLFOX will be evaluated at randomized phase 2 trial.

Timeline

Start
2026-06-01
Primary completion
2027-04-01
Completion
2028-04-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Irinotecan Small molecule 150 mg/m2
Subject Leucovorin Small molecule 100 mg/m2
Subject Leucovorin Small molecule 400 mg/m2
Subject Oxaliplatin Small molecule 85 mg/m2
Subject fluorouracil Small molecule 400 mg/m2
Subject fluorouracil Small molecule 2400 mg/m2

Indications