drugset / Trial / NCT07071961

Regorafenib (Reg) and Lorigerlimab (Lor), RELO Regimen, in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy [ReLOAD Trial]

NCT07071961

NaSingle-groupOpen-labelTreatment

Summary

To learn about the effects of the drugs regorafenib and lorigerlimab on circulating tumor DNA (ctDNA) in patients with CRC and who have radiographic occult minimal residual disease (MRD) after completing standard-of-care therapy

Timeline

Start
2026-02-11
Primary completion
2027-05-01
Completion
2029-05-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Lorigerlimab Protein / enzyme biologic Intravenous
Subject Regorafenib Small molecule Oral

Indications